There is an alarming increase in global incidence rates of thyroid nodules partially ascribed to the augmented use of ultrasonographs, while the effect of thyroid-disrupting environmental chemicals (TDC), such as, bisphenol A (BPA)- a plastic additive, or octyl-methoxy cinnamate (OMC)- an ultraviolet filter, on the etiology of thyroid nodular disease remains poorly understood. Commonly used food-contact materials, diet and personal care consumer products may contain BPA and OMC that both of them have been implicated with perturbations in thyroid hormonal homeostasis at low and environmentally-relevant human doses (Andra and Makris, 2012). Cyprus is among the countries with the highest thyroid cancer incidence rates. Although a relatively small percentage of the observed thyroid nodules (about 8-10%) may proceed to malignancy, the rest benign thyroid nodules present us with clinical symptoms requiring treatment.<\/p>\n
The\u00a0overall goal\u00a0of the\u00a0THYROCHEM\u00a0project is to explore associations between specific TDC and thyroid hormonal perturbations in a case-control sample of Cyprus and Romania.<\/p>\n","protected":false},"excerpt":{"rendered":"
There is an alarming increase in global incidence rates of thyroid nodules partially ascribed to the augmented use of ultrasonographs, while the effect of thyroid-disrupting environmental chemicals (TDC), such as, bisphenol A (BPA)- a plastic additive, or octyl-methoxy cinnamate (OMC)- … Continue reading