Use of metabolomics in refining the effect of an organic food intervention on biomarkers of exposure to pesticides and biomarkers of oxidative damage in primary school children in cyprus

- January 15 2022
Use of metabolomics in refining the effect of an organic food intervention on biomarkers of exposure to pesticides and biomarkers of oxidative damage in primary school children in cyprus

Key points:

  • Using the ORGANIKO trial, we coupled data from targeted measurements of pesticide metabolites and oxidative damage (OD) biomarkers with untargeted GC-MS metabolomics analysis with the aim to evaluate biological alterations associated with organic food consumption.
  • Changes in the metabolomic profile of primary school children were observed following a 40-day long systematic organic food intervention.
  • This is the first metabolomics study providing evidence of differentially expressed metabolites in an organic food intervention corroborating the reduction in biomarkers of OD in primary school children.

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